SS-31

Strengths & Pricing

Description

Elamipretide — investigated for mitochondrial function and oxidative stress research. Unlike most peptides in research, SS-31 doesn't bind a cell-surface receptor. Instead, it selectively concentrates in mitochondria — specifically at the inner mitochondrial membrane — where it interacts with cardiolipin, a phospholipid essential for electron transport chain (ETC) function. SS-31 is found at especially high concentrations in: Inner mitochondrial membrane — where it binds cardiolipin at ETC complex interfaces Cardiac mitochondria — the tissue with the highest mitochondrial density Skeletal muscle mitochondria — critical for exercise capacity and recovery Renal mitochondria — relevant to ischemia-reperfusion injury models Retinal mitochondria — studied in age-related macular degeneration